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Principal Scientist - CADD
Location:
Emeryville
Description:
About the role Hybrid About the role: This vital Computer-Aided Drug Discovery (CADD) role, located at our Emeryville, CA site, will join our talented and innovative drug discovery team. At Novartis, we value your ideas, personal growth and career aspirations. You will have opportunities to explore the power of cutting-edge science and technology in an environment that truly values multidisciplinary collaborations. Your key responsibilities: • Leverage your CADD expertise to engage and influence multidisciplinary project teams for effective decision-making from target identification through candidate nomination • Drive compound optimization cycles by participation in rational drug design and synthesis prioritization efforts via advanced scoring methods (active learning and ML model development, free-energy perturbation or alternate scoring method), in multi-objective fashion• Develop, improve and implement efficient computational workflows that can be distributed to our global CADD team• Initiate drug discovery efforts by proposing novel targets / modalities, evaluating target druggability and executing in silico hit generation, triage and expansion methodologies• Keep abreast of scientific developments and interact with internal and external scientists to integrate novel insights into computational approaches for drug discovery Commitment to Diversity & Inclusion: The Novartis Group of Companies are Equal Opportunity Employers and take pride in maintaining a diverse environment. We do not discriminate in recruitment, hiring, training, promotion or other employment practices for reasons of race, color, religion, gender, national origin, age, interactionual orientation, gender identity or expression, marital or veteran status, disability, or any other legally protected status. We are committed to building diverse teams, representative of the patients and communities we serve, and we strive to create an inclusive workplace that cultivates bold innovation. Visit ListedBuy for more information.
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